Albertas status of women minister joins Twitter debate over womens marches

first_imgEDMONTON – A minister in Alberta’s NDP government has chastised a tweet by the Opposition’s communications chair that slammed women’s marches held over the weekend.Status of Women Minister Stephanie McLean was responding to a Twitter post on Saturday from Sonia Kont of the United Conservative Party, who stated that “ideological marches like the one in Washington” do not empower women.Kont added that the last time she checked everyone had the same rights in society, and the march lacked clarity and purpose.McLean responded that the UCP “ridiculed the strength of women marching together in solidarity and using their voices fighting for equality.”Dozens of marches were held in communities across Canada on Saturday, a year after women’s marches that sprang up around the globe in the wake of Donald Trump’s inauguration as U.S. president.The event drew a large crowd at the provincial legislature in Edmonton, and an even larger one in Calgary.“What rights have women lost in the United States or Canada? It’s a shame these marches don’t say a word about the horrific conditions women face in the Middle East,” Kont tweeted in response to criticism of her initial posts.“Did this march also voice support for Iranian women or the Kurdish female heroes fighting ISIS? How about the Saudi Arabian women? They deserve rights and freedom too.”McLean, meanwhile, noted that women face a pay gap with men, are responsible for more childcare, make up only a fraction of corporate boards, and face other issues such as domestic violence.A number of people supported McLean on Twitter, including one who linked to a tweet by former prime minister Kim Campbell.“What I love about these marches are that they are everywhere,” Canada’s first and only female prime minister said. “And there are LOTS of great MEN smiling and marching with the women!”But there was also support for Kont, including a tweet from fellow UCP member Bettina Pierre-Gilles, who is listed on the party’s website as a member of its policy committee.“I couldn’t agree more with you Sonia. I’m a proud advocate for women and working our way to the top,” her tweet states.“These marches indeed only sends a message that only the loudest few can be heard, while nothing is advocated on policies.”UCP Leader Jason Kenney added his own voice to the discussion on Sunday evening.“Proud that the United Conservatives have so many strong, outspoken women as members. Our party doesn’t force conformity. Members are free to hold differing views,” Kenney tweeted.Canadian organizers said Saturday that 38 communities were hosting marches, rallies and other events.Police in Calgary tweeted their own support for the event in that city, along with a picture of a uniformed officer with marchers.“We were honoured to not only ensure the (march) was safe for all participants, but also to show our support by taking part,” the tweet from the Calgary Police stated.last_img read more

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Twitter critic site gone after Nebraska school district sues

OMAHA, Neb. — The Twitter account that has been criticizing about a southeast Nebraska school district since last fall disappeared shortly after the district filed a lawsuit seeking the critic’s identity.The person behind the anonymous @friend_bulldog account on Twitter posted another critical comment about the Friend School District Tuesday morning, but the account was gone by midday.The school district filed a lawsuit last week because officials want to learn who is behind the account. The district’s lawyer, Justin Knight, said the site has made false and defamatory statements about Superintendent David Kraus and other school officials.Knight says the district plans to continue pursuing the lawsuit .A Twitter spokeswoman didn’t immediately respond to questions about whether the social media company had removed the account.The Associated Press read more

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Applications for US unemployment benefits fall to 264000 lowest in 8 weeks

WASHINGTON – The number of Americans seeking unemployment benefits fell last week to the lowest level in two months, suggesting employers remain confident enough in the economy to hold onto their workers.The Labor Department said Thursday that weekly applications for unemployment aid dropped 11,000 to a seasonally adjusted 264,000. That’s the lowest level since July, when applications plunged to a 41-year low.Applications are a proxy for layoffs, so the decline indicates that employers are cutting fewer jobs. Americans are enjoying strong job security: Applications have been below 300,000 for the past six months, which hasn’t happened since 1973.Employers have also been hiring at a solid pace, adding an average of 243,000 a month in the past 12 months. That has brought the unemployment rate down to 5.1 per cent, a seven-year low.The health of the job market will play a crucial role in the Federal Reserve’s deliberations Thursday as it wraps up a two-day meeting. Fed policymakers may decide to raise the short-term interest rate they control for the first time in nine years.Some economists argue the job market has largely recovered from the Great Recession and can now withstand higher interest rates. But even so, many expect that other considerations, such as inflation that is stubbornly below the Fed’s target of a 2 per cent annual rate, may cause the Fed to hold off.Not all economists agree that hiring has fully recovered from the downturn. The number of people working part time but who would prefer full-time work is far higher than it was when the recession began in December 2007. And the percentage of Americans working or looking for work has fallen sharply since then.The number of people receiving benefits fell 26,000 to 2.24 million, the government said. That figure has declined 8.8 per cent in the past year. Many former recipients have gotten jobs, but some have used up all the benefits available to them. Applications for US unemployment benefits fall to 264,000, lowest in 8 weeks by Christopher S. Rugaber, The Associated Press Posted Sep 17, 2015 6:35 am MDT Last Updated Sep 18, 2015 at 1:20 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email FILE – In this July 15, 2015 file photo, Luigi Valdivieso, left, talks about job opportunities to Richard Solano at a job fair in Miami Lakes, Fla. The U.S. Labor Department reports on the number of people who applied for unemployment benefits the week ending Sept. 12, 2015. (AP Photo/Alan Diaz, File) read more

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SMMT Budget response

*An SMMT survey, commissioned in November 2004 among senior industry executives, showed that 95 per cent felt that the burden of legislation would add significant costs to their business in the next five years. Automotive Manufacturing – the Industry Perspective is available to download from http://lib.smmt.co.uk/articles/news/News/issues%20survey.pdfClick to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window) The industry had urged stability in taxation and greater clarity on incentives to promote cleaner fuel and vehicle technologies in its Budget submission. Today’s statement presented a mixed bag. SMMT today welcomed plans to introduce guidelines for the implementation of new EU regulations. The announcement by Chancellor Gordon Brown in his Budget, will reassure an industry which has consistently raised concerns about increases in the regulatory burden and the effect that ‘gold plating’ has on UK competitiveness.* Cleaner vehicle incentives SMMT is disappointed that the Chancellor failed to address concerns about cleaner vehicle incentives. Following the collapse of the Powershift scheme, manufacturers now need clear direction so they can plan for the introduction of the most environmentally friendly new vehicles. Government must address this urgently through dialogue with the industry on a new scheme based on stability and a technology-neutral approach. R&D Plans to enhance R&D tax credits have been welcomed by SMMT. The move should ensure that more companies in the automotive sector are encouraged to allocate greater resource to this key area. Chancellor follows industry lead on new car labelling The UK motor industry has taken a lead in producing better consumer information for new car buyers through its colour-coded label. Changing the way VED bands are categorised will now mirror the label’s A-F format, making the relationship between lower CO2 emissions and lower taxation clearer. SMMT is encouraged by the Chancellor’s decision to defer fuel duty rate rises until September 2005. However, with a volatile global oil market, the industry remains cautious about the cost burden that future ad hoc above inflation increases will bring for consumers after the election. Taxation SMMT has welcomed the freeze on corporation tax and the climate change levy. News that the minimum threshold for company car tax will be held at 140g/km of CO2 until 2007/08, has also been welcomed. It is a decision that brings long-term clarity to the new car fleet market. SMMT chief executive, Christopher Macgowan, commented, ‘This is news that will be widely welcomed by all motor manufacturers. Today’s commitment to a light regulatory touch follows improved dialogue between industry and the government and should prevent unnecessary burdens on a sector facing rising supply chain costs and exchange rate pressures.’ read more

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Reeva Steenkamp case Steroids found at Oscar Pistorius home reports

first_imgBANNED STEROIDS WERE reportedly found at the home where Oscar Pistorius is accused of murdering girlfriend Reeva Steenkamp.South African police are investigating whether Pistorius may have shot Steenkamp in an apparent episode of ‘roid rage’ – an aggressive outburst caused by the performance-enhancing drugs.“Steroid drugs were found at Pistorius’ home together with evidence of heavy drinking,” a source told The Sun. “That’s why police have specifically ordered that he be tested for steroids.”Police refused to respond to the claim today, though sources close to the investigation had previously told a local newspaper that the star Paralympian and Olympian’s blood was being tested for drugs. Steenkamp, 29, was shot dead on Thursday at Pistorius’ home in a secure housing estate near Pretoria.Police also reportedly found a bloodied cricket bat, though Pistorius’ family has strongly denied he intentionally killed Steenkamp. Pistorius, who remains in custody at a Pretoria police station, is due to appear at a bail hearing in court tomorrow.The hearing will be the first opportunity for the prosecution to detail the reasons why the 26-year-old double-amputee runner was charged with murder. Prosecutors allege the killing was premeditated.Further reports today claimed Reeva Steenkamp was shot in the hip in Pistorius’ bedroom before coming under further attack as she sought shelter in the bathroom.Meanwhile, Pistorius’ agent said his sponsors were committed, despite announcing that all upcoming races, including appearances in Sydney, Melbourne and Perth, had been cancelled.“All sponsors have given us their commitment towards Oscar, based on the relationships that they have formed with him over the past years,” Peet van Zyl said. “They are quite happy to allow the legal process to take its course before they make any other further and formal announcements on it.”RTÉ to block coverage of rugby internationals in NI from next year6 Nations update: Henry out for a month, O’Donnell and Madigan called uplast_img read more

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Nvidia believes Tegra 5 will outperform a PS3

first_imgMobile gaming has come on leaps and bounds over the last few years due in large part to the rate at which the hardware is improving. Each new generation brings with it a performance bump, which has seen the smartphones in our pockets and tablets in our bags manage near console-quality gaming.But how close to the current generation of consoles are mobile devices? According to Nvidia, the next generation of mobile processors will in fact outperform both a PlayStation 3 and Xbox 360.That claim has been made by Tony Tamsai, Nvidia’s senior vice president of content and technology. And going on the performance bump each generation of Nvidia’s Tegra chips has brought so far, he may have a point.The PS3 is rated at 200GFLOPS, where as the PS4 takes a massive leap forward to 1800GFLOPS. Now if you look at Nvidia’s mobile processors, the Tegra 3 ran at 12 GFLOPS, Tegra 4 is set to bring near 7x increase and will run at 80GFLOPS. So it’s actually quite a confident prediction to make that when Tegra 5 arrives it will easily achieve more than 200GFLOPS of performance.Looking at Nvidia’s release history, Tegra 2 launched in Q1 2010, Tegra 3 launched in Q1 2012, and Tegra 4 is set to launch in the next few months. So it’s safe to assume that Nvidia will be rolling out Tegra 5 at some point in mid-2015. If we see the same level of performance gain between Tegra 4 and 5 as seen between Tegra 3 and 4, then Nvidia should be getting close to PS4 performance levels by the time Tegra 6 is rolled out.But what Tegra won’t do for the foreseeable future is get anywhere near Nvidia’s top-of-the-line desktop graphics card the GeForce GTX Titan. With a rating of 4500GFLOPS, it’s by far the most powerful card on the market by a massive margin.last_img read more

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Gaz à effet de serre les forêts captent de moins en moins

first_imgGaz à effet de serre : les forêts captent de moins en moins de carboneVéritable poumons de la planète, les forêts stockent de moins en moins de carbone depuis une dizaine d’années. Un phénomène surprenant, quand dans les années 1990, le réchauffement climatique semblait favoriser la croissance des végétaux, et donc celle de leur absorption du dioxyde de carbone (CO2).Publiée dans la revue Science, une récente étude menée par des chercheurs de l’université du Montana, révèle que le stockage naturel de CO2 par la végétation tend à diminuer depuis les années 2000. Une conclusion tirée des analyses de données satellitaires de la NASA. Les travaux ont permis de constater que la végétation mondiale avait absorbé au cours des dix dernières années, 550 tonnes de carbone de moins que lors de la précédente période étudiée.   À lire aussiQui est Greta Thunberg, proposée pour un prix Nobel à seulement 16 ans ?En 2003 pourtant, de telles recherches avaient permis de constater qu’entre 1982 et 1999, le réchauffement climatique avait engendré une augmentation du stockage du dioxyde de carbone atmosphérique par les plantes. Leur croissance favorisée par les conditions climatiques, les végétaux absorbaient en captant d’importantes quantités de CO2.Mais de graves sécheresses ont touché l’Australie, l’Amérique du Sud et l’Afrique, où 70% des arbres ont capté moins de CO2 qu’habituellement au cours des dix dernières années. Une diminution que ne compense pas la tendance inverse observée dans l’hémisphère nord.Les auteurs de cette étude restent prudents quant aux conclusions qui peuvent être tirées de leurs travaux. S’ils estiment que “le changement climatique augmente la fréquence des grandes sécheresses régionales et cette tendance devrait se poursuivre dans un avenir proche”, ils soulignent que “le suivi des évolutions climatiques mondiales sera essentiel pour déterminer si la réduction observée du pouvoir de stockage des arbres constitue une simple variation décennale ou un véritable tournant de la séquestration terrestre du carbone.”Le 24 août 2010 à 20:02 • Emmanuel Perrinlast_img read more

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MacBook des batteries vulnérables

first_imgMacBook : des batteries vulnérables ?Le chercheur en sécurité américain Charlie Miller a mis au jour une nouvelle faille dans un système d’Apple. Ce sont cette fois les MacBook, et plus précisément leurs batteries, qui sont concernés. D’après celui-ci, le micro-contrôleur utilisé dans lesbatteries Lithium des ordinateurs portables d’Apple peut être compromis.Connu pour avoir mis au jour plusieurs failles dans les systèmes d’Apple, et notamment les iPhone 2G et 3GS, le chercheur en sécurité Charlie Miller assure avoir réussi à compromettre les ordinateurs portables MacBook, MacBook Pro, et MacBook Air. Sur le site blackhat.com, il explique que le micro-contrôleur des batteries des Mac portables peut devenir le vecteur de code malveillant.Ce micro-contrôleur est chargé de superviser les batteries, en lien avec l’ordinateur, l’interface graphique et l’usager. Il permet de réguler la consommation d’énergie de la machine, et indique le niveau de charge via une icône affichée sur l’écran de l’ordinateur. Or, cette communication permanente avec l’ordinateur constitue une menace de sécurité, comme Charlie Miller assure l’avoir démontré. Le hacker affirme avoir réussi à désactiver sept batteries de portables Mac, en obtenant les mots de passe protégeant le micro-contrôleur. Des problèmes de sécurité tels que “surcharge ou incendie” C’est grâce à l’analyse d’une mise à jour de 2009 obtenue avec la méthode de la rétro-ingénierie (reverse engineering) qu’il aurait découvert les mots de passe et ainsi réussi à reprogrammer des batteries. Une reprogrammation qui “peut suffire pour causer des problèmes de sécurité, tels que la surcharge ou un incendie” souligne Charlie Miller.Toutefois, d’après le site Clubic, le hacker pourrait présenter lors de la prochaine BlackHat Conference, un forum dédié aux professionnels de la sécurité IT, un outil permettant de modifier les mots de passe des batteries, et donc de prévenir d’éventuelles attaques.Le 27 juillet 2011 à 10:52 • Maxime Lambertlast_img read more

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HandsOn Sparklite Is a Fun ZeldaInspired Roguelike

HandsOn Sparklite Is a Fun ZeldaInspired Roguelike

first_img If you’ve read my work here on Geek.com or seen some of my tweets then you’ll know I’m not exactly a fan of roguelikes. I made this abundantly clear in my review of Rad. As I said in that write-up, though I don’t care for the genre, I’m always willing to try out new games to see if one clicks with me. I’m here to tell you that I have found this mythical roguelike with Sparklite. This title is the very definition of a surprise and one which I hope sets a new precedent for roguelikes.Though a roguelike at its core, Sparklite takes strong inspiration from The Legend of Zelda series. Specifically, games like A Link to the Past, The Minish Cap, and Link’s Awakening. Its top-down camera angle, screen transitions, map design, and pixel art hearken back to those classic Zelda titles. Of course, the big difference here is that Sparklite features randomly-generated maps and its own take on permadeath. These disperate elements serve to create a unique and satisfying experience.Sparklite stars a protagonist named Ada, who uses tools and gadgets to explore her strange world. Persistent earthquakes cause the land’s geography to constantly shift. This plot element is a genius way to explain the randomly-generated maps. Though the land changes, the one constant in this world is the sparklite element. With this, citizens power their floating cities and machinery. However, dangerous monsters, both great and small, stalk the land in search of the very sparklite Ada seeks.Core combat consists of melee attacks. In the demo I played, Ada used an upgradeable wrench to dispatch foes with a series of quick slashes. What spices up combat is the ability to dash. Some of the foes I faced, particularly the bosses, forced me to keep a steady finger over the dash button in case I had to make a quick escape. Considering how you’re thrown back into the main hub when you lose health, you’ll want to use dash to avoid any and all attacks if possible.Permadeath is a key feature of roguelikes. While Sparklite has a form of permadeath, it isn’t as punishing as it is in other titles. When enemies render Ada unconscious, she returns to the game’s hub world. You lose all progress with regard to missions. For example, if you found a quest item, you will lose it upon death and need to retrieve it again. What makes permadeath tolerable is that Ada remains as your main character and she gets to keep any and all collected sparklite. This is important since it prevents players from feeling frustrated over losing their progress upon death.The other key element that makes Sparklite digestible is the ability to upgrade. During my demo, I farmed to get 100 sparklite in order to upgrade my wrench’s attack. I died several times in the attempt but I rested assured knowing I’d always leave with some sparklite on every run. My persistence paid off when I eventually had enough sparklite to procure the desired upgrade. This encouraged me to brave the wilds instead of giving up in frustration.The randomly-generated maps I explored contained the same basic elements in different configurations. What I found interesting is how some maps seemed nearly identical to each other while others were wildly different. Since the land always changes, it is easy to lose one’s way. Thankfully, the in-game map always displays your objectives. This is a great feature that prevents players from wasting time wandering around looking for things to do.During my travels, I ran into a number of NPCs that gave me side quests. These quests are also randomly generated. For example, during one run, I found a boy seeking his lost sister. He tasked me with giving her half of a medallion. I died during the middle of the quest, thereby canceling it. On another run, I found the sister who gave me her half of the medallion. During this instance, I managed to find her brother and complete the quest. This approach to quests (like most of Sparklite) keeps subsequent runs feeling fresh.Along with weapons and health, you can upgrade your home base and turn it into a functioning society. After completing quests for NPCs, they’ll join your base and set up a workshop where you can purchase upgrades and equipment. This incentivizes players to scour each of the different maps looking for these useful characters. I didn’t get a full taste of this base building-ish aspect, but I can see myself becoming obsessed with finding every NPC I can. After all, every upgrade helps you survive the harsh world and shops are the only way to make that happen.The big highlight for me was the one boss battle I experienced. Taking place within a dark dungeon, I battled a giant mechanical foe whose main weapon was a ball and chain. Dodging the oncoming ball proved challenging but I managed to do so by studying the boss’ movements. The biggest challenge came when the ball began to suck in air. The trick to avoiding the powerful vacuum was to run instead of pressing dash. I didn’t get to defeat the boss, though I came close. The battle proved exhilarating and I can’t wait to see how inventive the other boss battles get.Sparklite is pure eye candy. Its bright, vibrant graphics recall the glory days of the 16-bit eras. Animations are buttery smooth and it’s easy to read enemy movements. Despite the random nature of maps, each has a life of its own. I mostly played within a forest, but the game also has other environments to explore. Even in an industry overflowing with “pixel art” games, Sparklite stands out with its distinctive and inviting graphics.Sparklite is the one roguelike I actually, well, like. Though I did enjoy Skyhill, Sparklite is more up my alley because of its overt nods to the 16-bit eras. It proudly wears its Zelda inspiration on its sleeves. Combat feels tight and responsive, while the randomly-generated maps keep players on their toes. The fact that you’re always making some kind of progress is what helps raise Sparklite above other roguelikes. I had a blast playing the demo and eagerly await the finished product. Sparklite is a winner in my book.Sparklite will release later in 2019. Pre-order it on Amazon.More on Geek.com:Hands-On: ‘Ghost Recon: Breakpoint’ Has Something for EverybodyReview: ‘Gears 5’ Brings a Fresh Perspective to the Franchise‘Oninaki’ Is an Interesting Game Marred by Poor Design Choices Sorry, You Can’t Date Keanu Reeves in ‘Cyberpunk 2077”Star Wars Pinball’ Has Your Favorite Brand in Ball Form Stay on targetlast_img read more

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San Diego County gas prices rise for first time in 35 days

San Diego County gas prices rise for first time in 35 days

first_img Posted: June 23, 2019 June 23, 2019 KUSI Newsroom KUSI Newsroom, Categories: Local San Diego News FacebookTwitter SAN DIEGO (KUSI) – The average price of a gallon of self-serve regular gasoline in San Diego County increased for the first time in 35 days today, rising two-tenths of a cent to $3.723.The average price had dropped for 34 consecutive days and 46 out of the last 47 days, including 1 cent on Saturday, according to figures from the AAA and Oil Price Information Service.It is 7.3 cents less than one week ago and 31.3 cents lower than one month ago, but 1.1 cents more than one year ago. San Diego County gas prices rise for first time in 35 dayslast_img

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Family offers £100000 and Michelinstar meals for livein nanny

Family offers £100000 and Michelinstar meals for livein nanny

first_imgSomething for the weekend: An annual salary of £100,000 may be enough to entice many of us to a demanding new role, but the perks offered by one family on the hunt for a live-in nanny go above and beyond this.A couple with four children aged two, five, seven, and 15 years old are recruiting a nanny with 15 years of experience and a degree in child psychology to work six days a week, from 7am to 8pm. The hours may be longer than a typical nine-to-five role but the nanny will enjoy meals cooked by a Michelin-star chef and can make use of the family’s cars: a Maserati, Porsche, and Range Rover.The successful candidate will also have opportunities for regular international travel, attending to the children across the family’s homes in Atlanta, Barbados, Cape Town, and London. The new nanny may be required to travel internationally up to three times a week.There are also learning and development opportunities, with employer-paid self-defence training provided to the new employee if they are not already skilled in this area.The children are home schooled and the nanny will be expected to support the children’s learning, which includes participating in their lessons where appropriate.The advert, which was posted on Childcare.co.uk, also specifies that the successful candidate sign a non-disclosure agreement and undergo a two-week probation period.The family updated the post on 25 August to note their surprise at the attention their advert had attracted. While this may have contributed to the volume of applications they have received – numbering more than 1,000 at 25 August – it appears this has not resulted in a high number of responses from candidates with the specifications they seek.At Employee Benefits, we can see why it might be difficult to recruit someone with the required experience and appetite for the role, but hopefully the compensation and benefits package on offer will help to attract the right candidate…last_img read more

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Thailand bus fire kills 20 Myanmar migrant workers

Thailand bus fire kills 20 Myanmar migrant workers

first_imgThailand Bus Fire. Photo:APA fire on a double-decker bus carrying migrant workers killed 20 people early Friday a week after another high death toll showed the continuing dangers of Thailand’s roads.The fire was reported to police around 1:30 am in Tak province in western Thailand along the border with Myanmar. The bus was heading to a factory in an industrial zone near Bangkok. Local media said the workers were from Myanmar.Police Lt. Raewat Aiemtak said 27 people managed to escape the fire, with one of them severely burned.The cause of the fire wasn’t immediately known, but Raewat said the driver reported the fire started in the middle of the bus and spread quickly. People in the front managed to escape but those in the back of the vehicle were trapped.On 21 March, a chartered tour bus lost control on a downhill curve in Thailand’s northeast and slid off the road, killing 18 people and injuring 33. A day later, a bus on a school trip in the central province of Ayutthaya skidded in the rain and flipped, injuring 39 people.Thailand has the second-highest rate of traffic fatalities in the world after Libya, according to World Health Organization statistics.last_img read more

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US brings back sanctions lifted after Iran nuclear deal

US brings back sanctions lifted after Iran nuclear deal

first_imgA man walks past an anti-US mural in Tehran, Iran on 13 October. Photo: ReutersThe leaders of Iran and the United States traded accusations Monday as the clock ticked down to Washington’s reimposition of sweeping sanctions on Tehran, which dismissed Donald Trump’s offer of talks on a new nuclear deal.After Trump told Iran to change its “destabilizing” behaviour or risk further economic isolation-while leaving the door open to negotiation-Iranian president Hassan Rouhani accused America of “psychological warfare.”The comments all came as Iran braces for the return of sweeping US sanctions on Tuesday-the first round, which takes effect overnight, targets the Islamic republic’s access to US banknotes and key industries including cars and carpets.Trump’s withdrawal from the historic 2015 nuclear accord in May infuriated his European partners, as many European businesses operating in Iran could find themselves on the wrong side of the US sanctions.“The Iranian regime faces a choice,” Trump said in a statement. “Either change its threatening, destabilizing behaviour and reintegrate with the global economy, or continue down a path of economic isolation.”“I remain open to reaching a more comprehensive deal that addresses the full range of the regime’s malign activities, including its ballistic missile program and its support for terrorism,” he added.But Rouhani was unimpressed with the offer.“If you’re an enemy and you stab the other person with a knife, and then you say you want negotiations, then the first thing you have to do is remove the knife,” the Iranian leader said in an interview on state television.“They want to launch psychological warfare against the Iranian nation,” Rouhani said. “Negotiations with sanctions doesn’t make sense.”Iran’s currency has lost around half its value since Trump announced the US would withdraw from the nuclear pact.That has ramped up tensions inside Iran, which has seen days of protests and strikes in multiple towns and cities over water shortages, high prices and wider anger at the political system.Severe reporting restrictions have made it impossible to verify the swirl of claims making their way through social media.Journalists did, however, confirm a heavy buildup of riot police and a mobile internet blackout Sunday night in the town of Karaj, just west of Tehran, which has been a focal point of unrest.European dismayThe second phase of US sanctions, which takes effect 5 November and will block Iran’s oil sales, is due to cause more damage, though several countries including China, India and Turkey have indicated they are not willing to entirely cut their Iranian energy purchases.The European Union’s diplomatic chief Federica Mogherini said the bloc, as well as Britain, France and Germany, deeply regretted Washington’s move.“We are determined to protect European economic operators engaged in legitimate business with Iran,” she said in a statement.Many large European firms are leaving Iran for fear of US penalties, and Trump warned of “severe consequences” against firms and individuals that continued to do business with Iran.Iran’s foreign minister Mohammad Javad Zarif told reporters the global reaction to Trump’s move showed that the US was diplomatically “isolated,” but acknowledged the sanctions “may cause some disruption.”Rouhani’s government has taken emergency measures to stem the collapse of the rial and brace for the return of sanctions.On Sunday, it eased foreign exchange rules, allowing unlimited tax-free currency and gold imports, and reopening exchange bureaus after a disastrous attempt to fix the value of the rial in April led to widespread black-market corruption.With senior religious authorities calling for a crackdown on graft, the judiciary said Sunday it had arrested the central bank’s foreign exchange boss, along with a government clerk and four currency brokers.The measures appeared to calm the markets, with the rial strengthening to 95,500 to the dollar-up a fifth on its record-low of 119,000 a fortnight ago.The US sees the sanctions “as a tool to pressure Iran to come back to the negotiating table to rehash the nuclear deal on terms more to Trump’s liking. That is not going to happen,” said John Glaser of the Cato Institute.Sanctions and talksTwo countries that have welcomed increased pressure on Iran are its key regional rivals, Israel and Saudi Arabia.Israeli prime minister Benjamin Netanyahu hailed the renewed sanctions as “an important moment for Israel, for the US, for the region, for the whole world.”There have been ongoing rumours that Trump and Rouhani could meet in New York in September at the United Nations General Assembly-though Rouhani reportedly rejected US overtures for a meeting at last year’s event.But that came less than a fortnight after a bellicose exchange between the two presidents, with Rouhani warning of the “mother of all wars” and Trump responding with a Twitter tirade against Iran’s “DEMENTED WORDS OF VIOLENCE.”last_img read more

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Author Talks the Lewis Cooking Gene with Michael Twitty

Author Talks the Lewis Cooking Gene with Michael Twitty

first_imgOn January 27th at 1p.m. come and discover the cooking legacy and ancestral roots of African American cuisine with food historian Michael Twitty, author of The Cooking Gene: A Journey Through African American Culinary History in the Old South. This illuminating memoir of Southern cuisine and food culture traces his ancestry through food, from Africa to America and slavery to freedom. A food sampling of African American cookery and book signing will follow. Register at https://www.eventbrite.com/e/author-talks-the-lewis-cooking-gene-with-michael-twitty-tickets-39921284637?aff=ebdssbcitybrowse.last_img

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Centre should take responsibility to bring down fuel prices Mamata

Centre should take responsibility to bring down fuel prices Mamata

first_imgKolkata: Chief Minister Mamata Banerjee on Thursday said the Centre should look into the issue of surging fuel prices not from a political angle but from a commoner’s point of view.The everyday rise in petrol and diesel prices is causing severe inconvenience to the common people, Banerjee said.Addressing a press conference after reaching Santiniketan on Thursday evening, she said: “All the political parties are urged to organise protest rallies against the steep rise in petrol and diesel prices.” Also Read – Heavy rain hits traffic, flightsShe is in Santiniketan to be a part of the Visva-Bharati convocation, where Prime Minister Narendra Modi and his Bangladesh counterpart Sheikh Hasina will also be present.Banerjee, who attended the swearing-in ceremony of JD(S) leader H D Kumaraswamy in Bengaluru on Wednesday, had a discussion over the issues with chiefs of most of the anti-BJP political parties who were also present during the oath-taking ceremony.Stating that there is need to initiate nationwide protests against the hike in petrol and diesel prices, Banerjee said: “I requested all to build up a protest against it. I spoke to Sonia Gandhi, Andhra Pradesh Chief Minister Chandrababu Naidu and former Chief Ministers of Uttar Pradesh Mayawati and Akhilesh Yadav in this connection. The discussion took place over tea after the oath-taking ceremony of HD Kumaraswamy.” Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedThis comes at the time when the Chief Minister has given a call for a one-is-to-one fight against the BJP in the 2019 general elections with all anti-BJP parties coming together to form a Federal Front.She said that it was the issue related to hike in prices of petrol and diesel for which her party had withdrawn support from the UPA government.When asked whether she would raise the issue with Prime Minister Narendra Modi during the convocation programme on Friday, she replied that it would not be the correct platform to do so. “But the issue will be raised if there is any opportunity for the same,” she said. Banerjee said petrol and diesel prices are at an all-time high and it would lead to harassment of common people as prices of essential goods would increase as well. “The prices of petrol and diesel are sky high and it will leave an adverse effect on the farmers,” she said, adding that her political party has already given a call for a statewide protest rally. There will be a rally in Kolkata on Friday and the statewide protest will take place on Saturday.last_img read more

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Win10 Security Plus review

Win10 Security Plus review

first_imgWin10 Security Plus review by Martin Brinkmann on April 14, 2016 in Software – Last Update: April 14, 2016 – 25 commentsWin10 Security Plus is a free tweak program for Microsoft’s Windows operating system that has a strong focus on security modifications.What may be confusing right from the get go is that it is compatible not only with Windows 10, but also previous versions of Windows all the way back down to Windows XP.Win10 Security Plus is a provided as a portable version that you can run from any location you desire after extracting the downloaded archive.Win10 Security PlusThe program displays all tweaks in a long list that you need to scroll to go through all of them. Each tweak is listed with its name and a checkbox, with the latter being used to change the state of the setting.While some tweaks are explained by the title, others are not, and that is one of the shortcomings of the program.For instance, what impact do changes to “restrict changes to Base System Objects”, “enable DEP for essential Windows programs & services” or “defer Windows upgrades” have?Most items are self-explanatory though, and features range from basic tweaks that you can do easily in Windows as well (show hidden files and folders), to modifying core Windows features such as Windows Update, Remote Registry or Windows Defender.What may be a bit confusing is that a checkmark may indicate that a feature is enabled or disabled, and that this becomes clear only when you read the title.For instance, there are checkmarks in “disable Remote Registry service” and “enable Windows Defender”.A checkmark indicates if “what the title mentions” is true or false, and not whether it is enabled or disabled.What’s good though is that the program checks the corresponding system settings and features, and either displays a checkmark or not according to those settings.Last but not least, you will notice that you cannot resize the program window to display more tweaks at the same time which means that you will only see part of the tweaks in the interface at all time.The majority of tweaks provided by Win10 Security Plus are valid for all versions of Windows.Once you check or uncheck boxes in the application window and hit apply, you are prompted to create a system restore point. That’s useful as it enables you to restore all settings should things turn out wrong.The program prompts you again after making the modifications to reboot the PC to apply the changes.What’s missing here is an option to restore settings directly from the program interface. That’s not a problem if you can remember the default states of each tweak, but problematic if you don’t.VerdictWin10 Security Plus is a portable program for Windows that you can run whenever you need to modify the 40 or so settings or features of the operating system.The software has some usability issues that I mentioned in the review but nothing that one could consider a deal breaker.Summary12345 Author Rating3.5 based on 6 votes Software Name Win10 Security PlusOperating System WindowsSoftware Category SystemLanding Page http://www.site2unblock.com/win10-security-plus/ Advertisementlast_img read more

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first_img Schoepf said iterative reconstruction substantially reduces the artifacts that arise from coronary calcifications and metallic stent struts that are present in filtered back projection. Videos | Radiation Therapy | July 30, 2019 VIDEO: Use of Radiotherapy to Noninvasively Ablate Ventricular Tachycardia Pierre Qian, MBBS, read more Schoepf said iterative reconstruction substantially reduces the artifacts that arise from coronary calcifications and metallic stent struts that are present in filtered back projection. Videos | Cardiac Imaging | July 30, 2019 VIDEOS | EP LAB | JULY 26, 2019 VIDEO: What Electrophysiologists Need From CT Imaging Prior to AF and VT Ablations Mark Ibrahim, M.D., F read more 12PreviousNext Siemens Healthcare received 510(k) clearance for ADMIRE (Advanced Modeled Iterative Reconstruction) in August. The combination of SAFIRE (Sinogram Affirmed Iterative Reconstruction), ADMIRE and the technology in the Somatom Force allows studies to be delivered at very low doses while maintaining image quality and preserving image impression.Over the past few years, iterative reconstruction has emerged as an alternative to filtered back projection with its ability to improve the image quality of computed tomography (CT) images. Although the clinical use of iterative reconstruction techniques in CT is rather new, U. Joseph Schoepf, M.D., professor of radiology, medicine and pediatrics, and director of the division of cardiovascular imaging at the Medical University of South Carolina in Charleston, said the technology itself has been around almost as long as CT imaging. “When the first CT scanner was conceived by Sir Godfrey Hounsfield — the inventor of CT — and the first system was actually put together by EMI, iterative reconstruction was the proposed reconstruction method for computed tomography,” he explained. Unfortunately, the technique was unable to gain widespread use in the clinical setting because of its slow processing time. Iterative reconstruction involves a complex process where software builds an image based on projection data generated by CT, and then revises it with reiterations to enhance image quality. Because computers in the 1970s — when CT scanners were created — were limited in their power, they could not withstand the demands of iterative reconstruction in the clinical setting. The technique was thus primarily used in nuclear imaging where simpler processing allowed for quicker generation of images. “Iterative reconstruction could be applied to more simple processing, but in order to apply it to much richer projection data that’s generated by computed tomography, the demands in terms of computer power were just too high for it to become a clinical reality,” Schoepf said. As iterative reconstruction algorithms were abandoned for CT, filtered back projection — a much faster, simpler, but less accurate data reconstruction method — became the gold standard. “You want an image fast, especially if you’re in an emergency or a trauma situation. So, filtered back projection has been used because it can produce images in a timely fashion and give results pretty much stat, but it makes a lot of assumptions about the data that may or may not be true for the sake of expediency,” Schoepf explained. Return of the ReconstructionAs computer power has increased over the last few years, however, the possibility of using iterative reconstruction algorithms in clinical CT has re-emerged. Today, all CT vendors offer iterative reconstruction, and most are introducing second generation algorithms. Iterative reconstruction algorithms can enhance the quality of CT in two ways. The first and the most common way is through iterative improvements that are mainly based in the image domain. This technique takes a CT image that is mostly acquired by filtered back projection and uses iterations to decrease the image noise and improve the quality of the image. Examples of these types of algorithms include ASiR (adaptive statistical iterative reconstruction) by GE Healthcare and IRIS (iterative reconstruction in image space) by Siemens Healthcare. Schoepf said that image-based techniques have shown to be very competitive in terms of time with filtered back projection, which takes roughly 1-2 minutes. “These iterative reconstruction techniques are capable of performing in high-pressure situations such as in an emergency, trauma, acute chest pain and so on,” he said. “The more image-based an iterative reconstruction algorithm is, the faster it is to reconstruct, and the higher the performance in terms of expediency and speed of reconstruction.” Going DeeperWhile image-based algorithms have reintroduced iterative reconstruction into the clinic, Schoepf predicted that larger benefits would come from the next generation of algorithms, including a technique called model-based reconstruction. “More impressive results can be garnered if you move into the actual raw data space of the projections,” he explained. “If you have your iterative reconstruction algorithm start at a point much earlier in the reconstruction process, then the benefits of the techniques obviously have a chance to come to play in a much stronger fashion because it doesn’t make that many assumptions about the data.” Examples of these types of algorithms include ADMIRE (advanced modeled iterative reconstruction) by Siemens and Veo by GE. Although these iterations have the power to greatly enhance CT image quality, some of them have not been widely adopted because they are still too slow for the clinical setting. “Those are algorithms that are based much deeper in the raw data space and thus take advantage of the capabilities of iterative reconstruction technique in a much more fundamental fashion, but some of them take much longer to reconstruct,” said Schoepf. Going forward, with improvement in technology, these more advanced algorithms will get faster and be available for widespread clinical use.  Benefits of Iterative ReconstructionPhysicians are already using image-based iterative reconstruction algorithms in many areas of healthcare because of the technology’s many advantages. The main advantage is the increase in image quality through the reduction of image noise. This has led to a reduction of radiation dose and, consequently, radiation exposure to patients. Schoepf noted that studies have shown that iterative reconstruction allows physicians to acquire the same image quality as filtered back projection with much lower radiation requirements. “The traditional way of reducing imaging noise on a computed tomography image was to increase the radiation dose,” Schoepf said. “If you have image reconstruction means, such as iterative reconstruction, to accomplish that goal, that reduces your radiation requirement.” Cardiovascular imaging is one area that has enthusiastically adopted iterative reconstruction because of these benefits. “In the cardiovascular system, filtered back projection causes blooming or beam hardening artifacts of high-density structures such as coronary artery calcifications or coronary artery stents,” said Schoepf, who presented on iterative reconstruction in cardiac imaging at the Society of Cardiovascular Computed Tomography’s (SCCT) 9th annual scientific meeting in July. “It makes it very difficult to gauge the significance of a blockage or narrowing of the heart vessels, and to determine if a stent that was deployed in the heart vessels of the patient is still patent or not.” Although iterative construction does not completely eliminate the problem, Schoepf said it substantially reduces the artifacts that arise from coronary calcifications and metallic stent struts, so physicians have a better chance of determining which narrowing of the coronary arteries is actually significant and whether stents are still patent. Adoption of Iterative ReconstructionSchoepf predicted that in a few years, iterative reconstruction will become the gold standard for CT image processing, noting that most physicians who continue to use filtered back projection in CT are doing so, in large part, because it is the traditional method. However, there are some circumstances preventing iterative reconstruction from spreading as rapidly as one may think based on the benefits of the technology alone. “The installed base of CT scanners that are out there and capable of employing iterative reconstruction techniques is not yet that large,” he explained. “This is a very recent development that has occurred over the past few years, and the majority of the CT scanners that are in the field do not offer the option of using iterative reconstruction.”As vendors like Siemens and GE continue to expand iterative reconstruction algorithms to make them faster, and as CT scanners in the field reach the end of their useful lives, hospitals and healthcare facilities will seek to purchase equipment that raises the bar for healthcare efficiency and lowers radiation dose.“The advantages of iterative reconstruction are just too overwhelming to not adopt it,” said Schoepf. “It is my prediction that within a couple of years, iterative reconstruction techniques will become the default method for image reconstruction with computed tomography and replace filtered back projection that has dominated that field for decades.” A transition that he said will be rapid. “As older CT systems are being swapped out by newer systems, the adaptation of iterative reconstruction techniques will just sky rocket, which, hopefully, should truly be associated with a tangible decrease in radiation exposure to the population,” Schoepf concluded.  FacebookTwitterLinkedInPrint分享 Videos | AAPM | July 29, 2019 VIDEO: Trends in Medical Physics at the AAPM 2019 meeting … read more Videos | Cardiac Imaging | July 30, 2019 VIDEO: The History of CT Calcium Scoring Arthur Agatston, M.D., clinical pro read more Sponsored Content | Case Study | Radiation Dose Management | August 13, 2019 The Challenge of Pediatric Radiation Dose Management Radiation dose management is central to child patient safety. Medical imaging plays an increasing role in the accurate… read more Siemens Healthcare received 510(k) clearance for ADMIRE (Advanced Modeled Iterative Reconstruction) in August. The combination of SAFIRE (Sinogram Affirmed Iterative Reconstruction), ADMIRE and the technology in the Somatom Force allows studies to be delivered at very low doses while maintaining image quality and preserving image impression. The CT scanner might not come with protocols that are adequate for each hospital situation, so at Phoenix Children’s Hospital they designed their own protocols, said Dianna Bardo, M.D., director of body MR and co-director of the 3D Innovation Lab at Phoenix Children’s. Videos | CT Angiography (CTA) | August 07, 2019 VIDEO: Walk Around of a Siemens Go.Top Dedicated Cardiac Scanner This is a quick walk around of the new Siemens Somatom Go.top cardiovascular edition compact computed tomography (CT) read more Video Player is loading.GE Cardiographe cardiac CT scanner at SCCT19Play VideoPlayMuteCurrent Time 0:00/Duration 0:38Loaded: 26.15%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:38 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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Videos | CT Angiography (CTA) | August 07, 2019 VIDEO: Walk Around of a GE Cardiographe Dedicated Cardiac CT Scanner This is a quick walk around of the GE Healthcare Cardiographe dedicated cardiac CT system on display at the… read more center_img Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 9:54Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -9:54 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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News | Artificial Intelligence | August 05, 2019 Montefiore Nyack Hospital Uses Aidoc AI to Spot Urgent Conditions Faster Montefiore Nyack Hospital, an acute care hospital in Rockland County, N.Y., announced it is utilizing artificial… read more Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 7:34Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -7:34 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 4:01Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -4:01 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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News | CT Angiography (CTA) | August 06, 2019 Artificial Intelligence Improves Heart Attack Risk Assessment When used with a common heart scan, machine learning, a type of artificial intelligence (AI), does better than… read more Feature | October 03, 2014 | Williette Nyanue (Re)introducing Iterative Reconstruction Increase in computer power paves way for the reintroduction of iterative reconstruction to clinical CT Siemens Go.Top CT scanner at SCCT19Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 1:05Loaded: 15.14%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -1:05 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button. Related Content Schoepf said iterative reconstruction substantially reduces the artifacts that arise from coronary calcifications and metallic stent struts that are present in filtered back projection. Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 5:23Loaded: 0.00%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -5:23 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button. Videos | Computed Tomography (CT) | July 30, 2019 VIDEO: New Advances in CT Imaging Technology Cynthia McColl… read more last_img read more

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Researchers Identify Ways to Predict and Avoid Radiotherapy Side Effects

Researchers Identify Ways to Predict and Avoid Radiotherapy Side Effects

first_img News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more News | Radiation Therapy | April 30, 2019 Researchers Identify Ways to Predict and Avoid Radiotherapy Side Effects Observing biomarkers and genetic changes could help radiation oncologists change dose or treatment plan to maximize efficacy while minimizing side effects News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more News | Pediatric Imaging | August 14, 2019 Ultrasound Guidance Improves First-attempt Success in IV Access in Children August 14, 2019 – Children’s veins read more Catalyst PT image courtesy of C-RAD Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications April 30, 2019 — New research has shown a combination of biological markers and certain genetic changes can predict radiation sensitivity and may help identify cancer patients more likely to suffer adverse side-effects after radiation therapy. In addition, the international team of researchers in the REQUITE project found further evidence to support an earlier finding in a smaller group of breast cancer patients that the time of day when radiotherapy is given can affect whether or not patients with particular gene variants suffer from adverse side effects.Results from the REQUITE project were presented at the 38th European Society for Radiotherapy and Oncology (ESTRO) Congress, April 26-30 in Milan, Italy.Chris Talbot, Ph.D., senior lecturer at the University of Leicester (UK), said that findings could help doctors to assess which patients were most likely to suffer from side effects of radiotherapy, and either change the radiation dose or plan other ways to avoid the side effects.”We know that patients vary in the way they respond to radiation treatment. Approximately 5 percent are sensitive to it and at risk of suffering side effects, but we don’t have a reliable way of identifying these patients. So radiation doses for all patients are currently limited by the risk of side effects in the most sensitive patients. This is the largest study to date to assess the use of biomarkers to predict radiotherapy-related toxicity,” he said.A total of 4,438 patients in 26 hospitals in eight countries — France, Germany, the U.S., Italy, Belgium, Spain, The Netherlands and the U.K. — enrolled in the REQUITE project, which started in 2014 and finished in September 2018. The patients had breast cancer (2,069 patients), lung cancer (561) or prostate cancer (1,808). Before receiving radiotherapy, they completed a short questionnaire and provided a blood sample that was analyzed for approximately 250,000 genetic variants called SNPs (single-nucleotide polymorphisms) in the complete genetic material of each patient (genome-wide), and a similar number of SNPs that are known to be associated with cancer.The researchers also tested for other biomarkers that might predict sensitivity to radiation treatment. One of these, called radiation-induced lymphocyte apoptosis (RILA), is a measure of the percentage of white blood cells (lymphocytes) that are killed by radiation.Talbot said, “A low percentage of radiation-induced cell death is associated with worse side effects, although we don’t know why this is. It may show that the state of the immune system on the day of radiotherapy is important.”Researchers followed up the patients until September 2018 to see who suffered short- or long-term adverse side effects; these included urinary problems or rectal bleeding for prostate patients, and pain or scar tissue in breast cancer patients.They found that people who smoked had fewer lymphocyte cells killed by radiation and, therefore, were likely to be at higher risk of side effects. Interim results after one year of follow-up had shown that RILA could predict longer-term side effects such as urinary problems in men with prostate cancer and worse scar tissue in breast cancer patients. However, as the researchers expected, the most recent analysis showed that RILA could not predict which patients would suffer acute adverse side effects — those that occur during or just after radiotherapy, such as the skin burn that occurs in some breast cancer patients. The exception was acute breast pain; low RILA predicted which breast cancer patients would be affected by this in the short term.”This suggests that acute breast pain may be caused by different biological mechanisms than other radiation-induced side effects,” said Talbot.Earlier analysis of 343 breast cancer patients from the REQUITE study and 535 patients from another study (Leicester, Nottingham and Derby [LeND] study) had found side effects from radiotherapy were affected by whether or not patients had a natural preference for the morning or the evening. Patients with variations in the PER3 or NOCT genes, which are associated with having an evening preference, had worse side effects if they received radiotherapy in the morning. The latest analysis of all the REQUITE patients has found that variations in these genes also have the same effect for acute diarrhoea in prostate cancer patients.”If these findings are confirmed, we could avoid side effects in patients simply by testing for these genes and then advising on the best time of day to be treated,” said Talbot. “We are currently working on the biological mechanisms involved, but in breast cancer patients we believe it is due to the timing of the division of skin cells.”He concluded: “Before these findings can be implemented in the clinic, we need to carry out further research in larger groups of patients and in more countries. Then we need to do a clinical trial to investigate timing of treatment and to show that this does, indeed, reduce the occurrence of adverse side effects.”Pierfrancesco Franco, M.D., Ph.D., associate professor in the Department of Oncology at the University of Turin, Italy, and chair of the ESTRO Young Committee, said, “This study is an elegant demonstration of how translational research potentially can help oncologists during the clinical decision-making process in order to offer patients a personalised approach that balances the need to control the tumour with the need to minimise the side effects on normal tissues, optimising radiotherapy treatment.”For more information: www.estro.org FacebookTwitterLinkedInPrint分享 News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more News | Neuro Imaging | August 16, 2019 ADHD Medication May Affect Brain Development in Children A drug used to treat attention-deficit/hyperactivity disorder (ADHD) appears to affect development of the brain’s… read more center_img The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more Images of regions of interest (colored lines) in the white matter skeleton representation. Data from left and right anterior thalamic radiation (ATR) were averaged. Image courtesy of C. Bouziane et al. News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more Related Content News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more Image courtesy of Imago Systems News | Patient Positioning Radiation Therapy | August 07, 2019 Qfix kVue One Proton Couch Top Validated by Mevion Medical Systems Qfix and Mevion Medical Systems announced that a special version of the kVue One Proton couch top is now both validated… read morelast_img read more

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REMAX Is Housing Finally In Recovery Mode

REMAX Is Housing Finally In Recovery Mode

first_img in Data, Origination, Servicing RE/MAX: Is Housing Finally In Recovery Mode? Agents & Brokers Home Prices Home Sales Housing Affordability Lenders & Servicers Processing RE/MAX Service Providers 2012-08-20 Tory Barringer August 20, 2012 455 Views center_img Looks like the dragon will have to step aside: 2012 is now “”The Year of the Housing Recovery,”” according to “”RE/MAX””:http://www.remax.com/.[IMAGE]The real estate giant released its National Housing Report for August 2012 (covering July), showing that both sales and prices have posted year-over-year increases for most of 2012. Home sales appear to have peaked year-to-date in June, with July’s sales falling 9.4 percent month-over-month. However, sales were up 10.3 percent from July 2011, marking the 13th consecutive month for year-over-year sales gains.Of the 53 metro areas surveyed by RE/MAX, 44 reported higher sales than one year ago, and 26 of those areas posted double-digit increases.The median sales price in July was $169,000, a 0.6 percent drop from June, but a 3.7 percent increase over July 2011. [COLUMN_BREAK]The increase marks the sixth straight month in which the median price outdid itself year-over-year.Forty-two of the 53 metro areas surveyed reported price increases over last year, 12 of which showed double-digit gains.””It’s reassuring that both sales and prices continue to rise higher on a yearly basis, indicating that this housing recovery is real,”” said “”Margaret Kelly””:http://www.remax.com/national-corp/biographies/margaret_kelly.aspx, RE/MAX CEO. “”Overall, the picture is getting brighter each month, but what we need for a sustainable recovery is a turn-around in unemployment and better availability of mortgages, especially for higher priced homes.””The average days on market for homes sold in July was 82, a two-day drop from June and a six-day drop year-over-year. July is only the second month since September 2011 with days on market below 90 and is the lowest average since July 2010.The drop in average days on market was attributed to low inventory. Inventory levels for July fell 5.4 percent from June and 26.8 percent from July 2011, marking the 25th consecutive month for shrinking month-to-month inventories.Given the current rate of sales, RE/MAX calculated the average months supply to be about 5.3, two months lower than the average 7.2 in July 2011.In the report, RE/MAX said falling inventory represents a major challenge to the recovery.””Inventory is now becoming a serious challenge to this recovering market, with available homes-for-sale falling 26.8 percent lower than the same month last year. Home sales could be much greater if more inventory was available, especially in the lower price range, where most sales are now occurring.”” Sharelast_img read more

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